Hepatoblastoma with Dr. Greg Tiao

There are around 250 new cases of hepatoblastoma per year.

Hemangioma is the most common liver lesion in children.

EOVIST is an MRI contrast agent that is taken up by hepatocytes and then excreted, providing the best definition when looking at the liver on imaging and distinguishing biliary anatomy.

Couinaud labeled the liver segments in a counterclockwise fashion after the districts of Paris, by injecting portal vessels.

The right hepatic vein differentiates the anterior sections (segments 5 and 8) from the posterior sections (segments 6 and 7) of the right liver.

The right portal vein separates superior segments (7 and 8) from inferior segments (5 and 6) in the right liver.

The change in practice for PRETEXT 3 and 4 tumors improved survival rates for patients with hepatoblastoma from less than 30% in the 1970s and 1980s to between 80 and 90% today.

PRETEXT 3 tumors should generally be biopsied at diagnosis and then started on neoadjuvant chemotherapy, with readiness to send patients to a transplant center or a center with expertise in advanced liver resections depending on response.

For PRETEXT 3 or 4 liver disease, specific indications for transplant include unresectable disease, unsafe resection, or resection that would leave the patient with an inadequate liver remnant.

Teams are now trained to recognize hepatoblastoma tumors and send them to centers that offer transplant or can do aggressive resection, resulting in more patient referrals than 15 years ago.

The FIT study has been ongoing for three years.