Safety and utility of long-acting steroid injection for management of post-operative stricture...

The study was published in 2026 in the Journal of Pediatric Surgery

The study examined institutional experience from 2018 to 2024

50 patients developed post-operative anastomotic stricture: 30 with anorectal malformations and 20 with Hirschsprung disease

70% of patients with anorectal malformations achieved stricture resolution with TAC injections

85% of patients with Hirschsprung disease achieved stricture resolution with TAC injections

The median number of TAC injections needed to achieve stricture resolution was 1 in both groups

30% of anorectal malformation patients required surgery despite TAC injections

10% of Hirschsprung disease patients required surgery despite TAC injections

There were no intraoperative complications from TAC injections

The 30-day complication rate was 2.2%

TAC injections may be a safe, minimally invasive adjunct to traditional dilations with promising rates of stricture resolution and low short-term morbidity

This is a retrospective single center study

TAC injections may be a useful treatment option before moving on to another operation