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Manejo expectante o ibuprofeno temprano para el tratamiento del conducto arterioso persistente
hosted by Dr. Cecilia Gigena
Educational content from recorded physician discussions — not medical advice. Talk to your (or your child's) care team about your situation.
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What the experts said
This is a multicenter non-inferiority study comparing extremely premature patients with persistent ductus arteriosus who received expectant management versus ibuprofen treatment.
The study enrolled 273 patients: 136 with expectant management and 137 with ibuprofen treatment.
Patients receiving expectant management had 17.6% necrotizing enterocolitis, 33.3% bronchopulmonary dysplasia, and 14% mortality.
Patients receiving ibuprofen treatment had 15.4% necrotizing enterocolitis, 50.9% bronchopulmonary dysplasia, and 18.6% mortality.
Expectant management appears to be non-inferior to ibuprofen treatment in extremely premature patients with persistent ductus arteriosus.