Live Event Content · Update Course 2023 - Updates in Pediatric Achalasia Management
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Video26 min·Published Aug 2023Older

Update Course 2023 - Updates in Pediatric Achalasia Management

With Dr. Mikhail Petrozan & Dr. Tim Kaine · hosted by Dr. Whit Holcomb
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What the experts said22 expert statements · 3 host summaries
The three types of achalasia (Chicago classification) all require the same treatment approach, but type 2 responds best to surgery while type 3 has the worst outcomes
Clinical
Type 3 achalasia does not respond well to treatments and recurrences happen much more frequently in patients with type 3
Clinical
The Eckardt score consists of four components: weight loss, dysphagia, chest pain, and regurgitation, used both for diagnosis and clinical follow-up
ClinicalMikhail Petrozan
At Children's National, fundoplication is not offered with Heller myotomy because anterior wraps have caused esophageal torquing as children grow, requiring takedown of the wrap
Clinical
Approximately 50% of pediatric achalasia patients have had some intervention (dilation or Botox) before definitive surgery
EpidemiologicalTim Kaine
Botox injection causes significant scar tissue formation, while prior dilations cause minimal fibrosis that is not problematic during surgery
ClinicalTim Kaine
Pediatric patients biopsied one year after POEM showed a reflux rate of approximately 5%, compared to 50% in adult POEM patients
EpidemiologicalMikhail Petrozan
The standard myotomy extends approximately 2 centimeters onto the stomach and 4-5 centimeters up the esophagus, for a total average length of 6-7 centimeters
ClinicalTim Kaine
Symptoms within one year after myotomy suggest incomplete myotomy, while later recurrence may represent true recurrent achalasia related to growth
OpinionTim Kaine
Manometry in achalasia patients often continues to show abnormal findings even after successful treatment, making it less useful for post-operative surveillance
ClinicalMikhail Petrozan
Endoflip measures esophageal distensibility and diameter, providing real-time feedback during myotomy to determine adequacy of the procedure
Clinical
The first human POEM case was performed by Inoue in 2010
Clinical
Children's National performed their first POEM in 2015 after a two-year process to obtain equipment, with initial cases having conversion to Heller as backup
Clinical
POEM offers 360 degrees of myotomy options compared to approximately 180 degrees with laparoscopic Heller, and avoids hiatal dissection which reduces reflux risk
Clinical
In the Children's National series of 73 POEM cases, the re-intervention rate requiring balloon dilation within one year was 15%, similar to their historical Heller experience
EpidemiologicalTim Kaine
Five redo POEM procedures were performed, with three of the five being in patients with type 3 achalasia who presented with recurrent symptoms within one year
EpidemiologicalTim Kaine
In the Children's National POEM series, 11% were type 3 achalasia (higher than most literature), 62% were type 2, with type 2 patients having the best outcomes
EpidemiologicalTim Kaine
Type 2 achalasia patients have essentially no peristalsis, so opening the LES allows them to swallow effectively, while type 1 patients have spastic esophagus causing more persistent symptoms
ClinicalTim Kaine
Children's National currently performs approximately 15 POEM procedures per year, with initial years having much lower volumes (2-3 cases)
Epidemiological
Only approximately 10% of pediatric surgeons perform thoracoscopic tracheoesophageal fistula repair, illustrating the challenge of disseminating advanced techniques
EpidemiologicalWhit Holcomb
Many patients are now specifically requesting POEM after doing their own research, rather than considering Heller myotomy
OpinionWhit Holcomb
The POEM technique has been successfully adapted for pyloric myotomy (G-POEM) in gastroparesis patients
Clinical
A 2015 IPEG survey showed 95% of pediatric surgeons would perform fundoplication with Heller myotomy
Host summaryTim Kaine summarizing the discussion · not cited in answers
In adult literature, when Heller myotomy is performed, good evidence shows fundoplication is not necessary
Host summaryTim Kaine summarizing the discussion · not cited in answers
The learning curve for POEM is approximately 20 cases, with mastery around 60 cases according to adult literature
Host summaryThe host summarizing the discussion · not cited in answers