Journal of Pediatric Article Review: June 2023, AAP Issue

Proximal small bowel resection results in greater oxidative stress in the liver, evidenced by elevated mRNA transcripts for tumor necrosis factor alpha, NADPH oxidase, and glutathione synthase with greater compensatory antioxidant response

46 of 50 hepatoblastoma patients underwent resection using adjuvant techniques including total hepatic vascular exclusion, vascular reconstruction, biliary reconstruction, or en-bloc resection and total hepatectomy with transplantation

82% (41 of 50) of hepatoblastoma patients were able to achieve no-evidence-of-disease (NED) status

14 high-risk hepatoblastoma patients underwent a median of 2.5 pulmonary metastasectomies (7 for unilateral disease, 7 for bilateral disease) with a median of 4.5 nodules resected

5 high-risk hepatoblastoma patients relapsed and 3 of them were saved; NED status was inversely correlated with 5-year mortality

The esophageal atresia surveillance survey had a 77% response rate from 181 physicians at 19 institutions

Only 36% of institutions perform routine upper GI endoscopy in esophageal atresia patients regardless of symptoms, despite evidence showing these patients should be surveilled

Without proper surveillance, esophageal atresia patients could be at risk for esophageal cancer and chronic dysmotility as they survive into adulthood