Chiara Oreglio

60 timestamped statements across 2 topics — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Featured statements

▶ Ep 1 · 6:48
it's not like a strut bar is very rigid and it obliges the surrounding the surrounding ribs to be stick to it and then and thus it modifies the shape of the chest wall leading to what it's the most common complication after that it is scoliosis or deformation of chest wall
quote · Ewing Sarcoma
▶ Ep 1 · 6:48
compared to very rigid structures such as the titanium bars, the strut bar, the bioprosthesis integrates with the tissue. Therefore, it's the tissue while the surrounding tissue grows, it also grows with it
quote · Ewing Sarcoma
▶ Ep 556 · 0:00
reaching what we call the drum like tension, that is a tension strong enough to guarantee internal organ protections while accommodating with the chest wall growing process
quote · Pediatric Oncology
▶ Ep 556 · 0:00
primary chest wall tumors are a rare entity in pediatric population with wingsarcoma being the most common one
quote · Pediatric Oncology

Nothing matches these filters — clear the search or widen the filters.

Chiara's statements about Ewing Sarcoma 30 statements

Open the Ewing Sarcoma collection →

Dr. Chiara Oreglio - Best of the Best in Pediatric Surgery 2025

▶ Ep 1 · 0:00
epidemiological Primary chest wall tumors are a rare entity in pediatric population with Ewing sarcoma being the most common one. ↗
▶ Ep 1 · 0:00
guideline Surgery remains the mainstay of treatment for primary chest wall tumors, composed of a demolitive phase and a reconstructive phase. ↗
▶ Ep 1 · 0:00
clinical No limitations of movement are reported by any of the patients. ↗
▶ Ep 1 · 0:00
clinical Permacol can be associated with other synthetic materials in hybrid reconstruction. ↗
▶ Ep 1 · 0:00
clinical The material of choice for chest wall reconstruction must encompass features of both stiffness and malleability while being biologically compatible. ↗
▶ Ep 1 · 0:00
clinical The reconstructive material must be able to physiologically integrate with tissues and cope with the ongoing growing process in pediatric patients. ↗
▶ Ep 1 · 0:00
epidemiological The series includes the youngest patient affected by chest wall Ewing sarcoma reported in literature, an 18-month-old female. ↗
▶ Ep 1 · 0:00
clinical The institution used porcine acellular dermal collagen (Permacol) for chest wall reconstruction. ↗
▶ Ep 1 · 0:00
clinical Three patients were treated: two males and one female (18 months old at diagnosis). ↗
▶ Ep 1 · 0:00
clinical The surgical technique aims for 'drum-like tension'—tension strong enough to guarantee internal organ protection while accommodating chest wall growth. ↗
▶ Ep 1 · 0:00
clinical A latissimus dorsi muscular flap is created, rotated, and fixated over the prosthesis with sparing of the thoracodorsal artery. ↗
▶ Ep 1 · 0:00
clinical In all patients, at least three ribs were removed in accordance with oncological guidelines. ↗
▶ Ep 1 · 0:00
clinical In two cases, there was diaphragmatic involvement that was removed and reconstructed with Permacol. ↗
▶ Ep 1 · 0:00
clinical In one case with a large defect, two Stratos bars (rigid material) were used in addition to Permacol, instead of the usual four bars. ↗
▶ Ep 1 · 0:00
clinical None of the patients reported any perioperative complications according to the Clavien classification. ↗
▶ Ep 1 · 0:00
clinical R0 resection was reached in all cases. ↗
▶ Ep 1 · 0:00
clinical All patients were able to restart chemotherapy within two months from surgery. ↗
▶ Ep 1 · 0:00
clinical The youngest case shows no paradoxical chest wall movement at follow-up and is disease-free. ↗
▶ Ep 1 · 0:00
opinion Permacol mesh presents good adaptability to the growing process with a reduced risk of rejection and infection. ↗
▶ Ep 1 · 0:00
clinical Permacol is highly versatile for reconstruction of highly mobile tissues such as the diaphragm. ↗
▶ Ep 1 · 0:00
clinical The thickness of the Permacol mesh can be adjusted according to age, region to be reconstructed, and defect size, making it feasible even in very young children. ↗
▶ Ep 1 · 0:00
quote primary chest wall tumors are a rare entity in pediatric population with wingsarcoma being the most common one ↗
▶ Ep 1 · 0:00
quote reaching what we call the drum like tension, that is a tension strong enough to guarantee internal organ protections while accommodating with the chest wall growing process ↗
▶ Ep 1 · 0:00
quote we our practice should be simple and at least as least invasive as possible and we must always remember that we should dismantle illnesses without dismantling the patient's identity ↗
▶ Ep 1 · 6:48
quote it's not like a strut bar is very rigid and it obliges the surrounding the surrounding ribs to be stick to it and then and thus it modifies the shape of the chest wall leading to what it's the most common complication after that it is scoliosis or deformation of chest wall ↗
▶ Ep 1 · 6:48
quote compared to very rigid structures such as the titanium bars, the strut bar, the bioprosthesis integrates with the tissue. Therefore, it's the tissue while the surrounding tissue grows, it also grows with it ↗
▶ Ep 1 · 6:48
clinical Compared to rigid structures like titanium bars or Stratos bars, bioprosthesis integrates with tissue and grows with surrounding tissue as the patient grows. ↗
▶ Ep 1 · 6:48
clinical Rigid bars like Stratos bars oblige surrounding ribs to remain fixed, modifying chest wall shape and leading to scoliosis or chest wall deformation as the most common complication. ↗
▶ Ep 1 · 6:48
clinical The oldest patient treated with Permacol did not develop any difficulty in movement, and imaging shows the rib cage is not deformed. ↗
▶ Ep 1 · 6:48
clinical With bioprosthesis, tissues are free to grow in their own way without chest wall deformity. ↗
Chiara's statements about Pediatric Oncology 30 statements

Open the Pediatric Oncology collection →

Dr. Chiara Oreglio - Best of the Best in Pediatric Surgery 2025

▶ Ep 556 · 0:00
clinical In all patients, at least three ribs were removed in accordance with oncological guidelines. ↗
▶ Ep 556 · 0:00
clinical Permacol is highly versatile for reconstruction of highly mobile tissues such as the diaphragm. ↗
▶ Ep 556 · 0:00
clinical The thickness of the Permacol mesh can be adjusted according to age, region to be reconstructed, and defect size, making it feasible even in very young children. ↗
▶ Ep 556 · 0:00
clinical Permacol can be associated with other synthetic materials in hybrid reconstruction. ↗
▶ Ep 556 · 0:00
quote primary chest wall tumors are a rare entity in pediatric population with wingsarcoma being the most common one ↗
▶ Ep 556 · 0:00
quote reaching what we call the drum like tension, that is a tension strong enough to guarantee internal organ protections while accommodating with the chest wall growing process ↗
▶ Ep 556 · 0:00
quote we our practice should be simple and at least as least invasive as possible and we must always remember that we should dismantle illnesses without dismantling the patient's identity ↗
▶ Ep 556 · 0:00
epidemiological Primary chest wall tumors are a rare entity in pediatric population with Ewing sarcoma being the most common one. ↗
▶ Ep 556 · 0:00
guideline Surgery remains the mainstay of treatment for primary chest wall tumors, composed of a demolitive phase and a reconstructive phase. ↗
▶ Ep 556 · 0:00
clinical The material of choice for chest wall reconstruction must encompass features of both stiffness and malleability while being biologically compatible. ↗
▶ Ep 556 · 0:00
clinical The reconstructive material must be able to physiologically integrate with tissues and cope with the ongoing growing process in pediatric patients. ↗
▶ Ep 556 · 0:00
epidemiological The series includes the youngest patient affected by chest wall Ewing sarcoma reported in literature, an 18-month-old female. ↗
▶ Ep 556 · 0:00
clinical The institution used porcine acellular dermal collagen (Permacol) for chest wall reconstruction. ↗
▶ Ep 556 · 0:00
clinical Three patients were treated: two males and one female (18 months old at diagnosis). ↗
▶ Ep 556 · 0:00
clinical The surgical technique aims for 'drum-like tension'—tension strong enough to guarantee internal organ protection while accommodating chest wall growth. ↗
▶ Ep 556 · 0:00
clinical A latissimus dorsi muscular flap is created, rotated, and fixated over the prosthesis with sparing of the thoracodorsal artery. ↗
▶ Ep 556 · 0:00
clinical In two cases, there was diaphragmatic involvement that was removed and reconstructed with Permacol. ↗
▶ Ep 556 · 0:00
clinical In one case with a large defect, two Stratos bars (rigid material) were used in addition to Permacol, instead of the usual four bars. ↗
▶ Ep 556 · 0:00
clinical None of the patients reported any perioperative complications according to the Clavien classification. ↗
▶ Ep 556 · 0:00
clinical R0 resection was reached in all cases. ↗
▶ Ep 556 · 0:00
clinical All patients were able to restart chemotherapy within two months from surgery. ↗
▶ Ep 556 · 0:00
clinical No limitations of movement are reported by any of the patients. ↗
▶ Ep 556 · 0:00
clinical The youngest case shows no paradoxical chest wall movement at follow-up and is disease-free. ↗
▶ Ep 556 · 0:00
opinion Permacol mesh presents good adaptability to the growing process with a reduced risk of rejection and infection. ↗
▶ Ep 556 · 6:48
clinical With bioprosthesis, tissues are free to grow in their own way without chest wall deformity. ↗
▶ Ep 556 · 6:48
clinical Compared to rigid structures like titanium bars or Stratos bars, bioprosthesis integrates with tissue and grows with surrounding tissue as the patient grows. ↗
▶ Ep 556 · 6:48
clinical Rigid bars like Stratos bars oblige surrounding ribs to remain fixed, modifying chest wall shape and leading to scoliosis or chest wall deformation as the most common complication. ↗
▶ Ep 556 · 6:48
clinical The oldest patient treated with Permacol did not develop any difficulty in movement, and imaging shows the rib cage is not deformed. ↗
▶ Ep 556 · 6:48
quote it's not like a strut bar is very rigid and it obliges the surrounding the surrounding ribs to be stick to it and then and thus it modifies the shape of the chest wall leading to what it's the most common complication after that it is scoliosis or deformation of chest wall ↗
▶ Ep 556 · 6:48
quote compared to very rigid structures such as the titanium bars, the strut bar, the bioprosthesis integrates with the tissue. Therefore, it's the tissue while the surrounding tissue grows, it also grows with it ↗