38 timestamped statements
across 3 topics
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Featured statements
▶Ep 1 · 11:47
It's a catheter that stays in that essentially numbs the abdominal uh wall and essentially allows them to get up, move, um they'll pass gas that same day because they're not really using any narcotic medication and we just schedule ibuprofen and Tylenol with it.
GNRH agonist therapy was something that we did, I mean, I would say not within the most recent years to try to decrease uh fertility uh or increase fertility preservation during chemotherapy. It really has not demonstrated any clear preservation uh for patients.
Um, most of the data though is from post pubertal patients. But there have been studies to actually look at the ovarian tissue when we pull it out of the pediatric patients and there's visible visible follicles.
Julie Rios gives fewer narcotics to adult patients, using acetaminophen and ibuprofen, and sends them home with a few oxycodone tablets as breakthrough for one or two days.
clinicalJulie Rios gives fewer narcotics to adult patients, using acetaminophen and ibuprofen, and sends them home with a few oxycodone tablets as breakthrough for one or two days.↗
quoteI give a few and it's just the oxycodone by itself.↗
▶Ep 1 · 11:47
clinicalTAP blocks involve medicine that goes intercostally with a catheter that numbs the abdominal wall, allowing patients to get up, move, and pass gas the same day without narcotic medication.↗
▶Ep 1 · 11:47
quoteIt's a catheter that stays in that essentially numbs the abdominal uh wall and essentially allows them to get up, move, um they'll pass gas that same day because they're not really using any narcotic medication and we just schedule ibuprofen and Tylenol with it.↗
Julie's statements about Pediatric Oncology28 statements
quoteUm, but again, if we don't recommend this as our first line, Asco does not recommend this as first line.↗
▶Ep 156 · 1:08
quoteAnything over 15 in a pediatric patient puts them at high risk for ovarian failure in the future.↗
▶Ep 156 · 1:08
quoteGNRH agonist therapy was something that we did, I mean, I would say not within the most recent years to try to decrease uh fertility uh or increase fertility preservation during chemotherapy. It really has not demonstrated any clear preservation uh for patients.↗
▶Ep 156 · 1:08
guidelineGnRH agonist therapy has not demonstrated clear fertility preservation benefit in pediatric patients and is not recommended as first-line by ASCO.↗
▶Ep 156 · 1:08
clinicalGnRH agonist therapy may have some benefit in older patients with breast cancer, though studies conflict.↗
▶Ep 156 · 1:08
clinicalOvarian tissue cryopreservation is experimental and followed by future ovarian tissue transplantation, allowing about 30% of patients to have fertility.↗
▶Ep 156 · 1:08
clinicalMost fertility data from ovarian tissue transplantation comes from post-pubertal patients, but studies show visible follicles in tissue from pediatric patients.↗
▶Ep 156 · 1:08
clinicalOvarian tissue is typically cryopreserved within the same day of harvest to minimize egg loss from lack of vascular supply.↗
▶Ep 156 · 1:08
clinicalOrthotopic transplantation involves placing tissue back where the ovary was removed, either sewn to the contralateral ovary or in a peritoneal pocket near the fallopian tube.↗
▶Ep 156 · 1:08
epidemiologicalMeta-analysis data shows 37-50% of patients with transplants had live births, with 30-40% achieving fertility preservation (some requiring multiple transplants).↗
▶Ep 156 · 1:08
epidemiological60-90% of patients with ovarian tissue transplants achieve restoration of ovarian endocrine function.↗
▶Ep 156 · 1:08
clinicalOvarian transposition may not provide adequate distance from scatter radiation in young patients receiving pelvic radiation.↗
▶Ep 156 · 1:08
quoteUm, most of the data though is from post pubertal patients. But there have been studies to actually look at the ovarian tissue when we pull it out of the pediatric patients and there's visible visible follicles.↗
▶Ep 156 · 1:08
clinicalThe patient's CED was 30.8 grams per meter squared, placing her at high risk for primary ovarian insufficiency.↗
▶Ep 156 · 1:08
quoteUm, we typically do it within the same day to try to minimize any loss of eggs just from being out of their vascular supply.↗
▶Ep 156 · 1:08
clinicalCyclophosphamide equivalent dose (CED) over 15 grams per meter squared puts pediatric patients at high risk for ovarian failure.↗
▶Ep 156 · 7:26
clinicalOvarian tissue cryopreservation became standard of care first in the Netherlands.↗
▶Ep 156 · 7:26
clinicalOvarian tissue cryopreservation requires both a surgeon to remove tissue and facilities to freeze it on-site.↗
▶Ep 156 · 8:42
clinicalSperm banking is only an option for post-pubertal males, typically Tanner stage 3 and above.↗
▶Ep 156 · 8:42
clinicalFor prepubertal males receiving high-dose treatment, testicular tissue cryopreservation is available through protocols such as at University of Pittsburgh.↗
▶Ep 156 · 8:42
clinicalTesticular tissue preservation typically involves a wedge biopsy rather than full orchiectomy.↗
▶Ep 156 · 8:42
clinicalOvarian tissue transplantation is typically performed only when pregnancy is desired because the graft lasts only 2-5 years.↗
▶Ep 156 · 8:42
clinicalHormone replacement medication is used for pubertal induction and hormone support until pregnancy is desired.↗
▶Ep 156 · 8:42
quoteSo it only is going to last somewhere between two and five years is what the studies show.↗
▶Ep 156 · 10:58
clinicalHospital fees and anesthesia fees can often be covered by insurance when ovarian tissue harvest is combined with other oncology procedures like bone marrow biopsy or central line placement.↗
▶Ep 156 · 10:58
clinicalMost centers now use long-term storage facilities with three or four mechanisms for detecting tank dysfunction to prevent tissue loss.↗
▶Ep 156 · 10:58
quoteSo most of the long-term storage facility has three or four mechanisms for detecting tank dysfunction so that that doesn't happen.↗
▶Ep 156 · 10:58
clinicalTissue storage costs are income-dependent: $75 per year for oncology patients below income threshold, $275 per year above threshold.↗
Julie's statements about Umbilical Hernia5 statements
clinicalJulie Rios gives fewer narcotics to adult patients, using acetaminophen and ibuprofen, and sends them home with a few oxycodone tablets as breakthrough for one or two days.↗
quoteI give a few and it's just the oxycodone by itself.↗
▶Ep 2 · 11:47
quoteIt's a catheter that stays in that essentially numbs the abdominal uh wall and essentially allows them to get up, move, um they'll pass gas that same day because they're not really using any narcotic medication and we just schedule ibuprofen and Tylenol with it.↗
▶Ep 2 · 11:47
clinicalTAP blocks involve medicine that goes intercostally with a catheter that numbs the abdominal wall, allowing patients to get up, move, and pass gas the same day without narcotic medication.↗
