Seth Goldstein

94 timestamped statements across 2 topics — auto-found in recorded discussions, each timestamp jumps to the exact moment.

Featured statements

▶ Ep 2 · 16:20
when the stent is emitting an infrared light that gets picked up by your system and you know that that travels through centimeters of tissue. It, it's clear as day.
quote · Hepatocellular Carcinoma
▶ Ep 3 · 2:12
Pediatric surgeons can I'm not yet to the point of saying should but can consider use of ICG as an adjunct to sentinel node identification.
quote · Hepatocellular Carcinoma
▶ Ep 447 · 8:40
In children under 10 years old with paratesticular rhabdomyosarcoma, sentinel node biopsy may be performed instead of full ipsilateral lymph node clearance
guideline · Pediatric Oncology
▶ Ep 447 · 1:36
Sentinel node biopsy in pediatric rhabdomyosarcoma is standard of care and dictates drug regimen and indicates radiation to lymph node basin if positive
guideline · Pediatric Oncology

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Seth's statements about Hepatocellular Carcinoma 47 statements

Open the Hepatocellular Carcinoma collection →

Update Course 2023 - Updates in the use of ICG

▶ Ep 2 · 0:28
quote my understanding was that this distinguished course had already taken on ICG in some of its better known uses, namely organ. Angiography and expatic biliary tree identification. So I was asked to take a little bit of an approach for how, how, how would you use it for pediatric surgical oncology. ↗
▶ Ep 2 · 1:36
guideline Sentinel node biopsy in pediatric rhabdomyosarcoma is standard of care and dictates drug regimen and indicates radiation to lymph node basin if positive ↗
▶ Ep 2 · 1:36
quote This is pretty much standard of care. It, it dictates to some extent the drug regimen. It'll, it'll indicate radiation to the lymph node basin if it's positive. ↗
▶ Ep 2 · 3:16
clinical ICG can be used as an adjunct to sentinel node identification in pediatric surgical oncology ↗
▶ Ep 2 · 3:16
quote pediatric surgeons can, uh, I'm not yet to the point of saying should, but can consider use of ICG as an adjunct to the sentinel node identification ↗
▶ Ep 2 · 4:00
clinical ICG technique allows real-time intraoperative control of injection location (intratumoral vs. four quadrants, dermal vs. subdermal) by surgeons rather than radiologists ↗
▶ Ep 2 · 4:30
quote the ICG technique is real-time in the operating room ↗
▶ Ep 2 · 5:20
clinical ICG fluorescence visualization occurs over 45-75 seconds after injection, allowing direct observation of lymphatic drainage to sentinel node ↗
▶ Ep 2 · 8:40
guideline In children under 10 years old with paratesticular rhabdomyosarcoma, sentinel node biopsy may be performed instead of full ipsilateral lymph node clearance ↗
▶ Ep 2 · 8:40
clinical ICG enables laparoscopic sentinel node identification in paratesticular rhabdomyosarcoma, which is not feasible with radiotracer methods ↗
▶ Ep 2 · 8:40
quote what about the stuff you can't do with technicium like laparoscopy? ↗
▶ Ep 2 · 9:47
quote Into cyanin green was this neat dye that uh that the, the post World War II Kodak company found because it's got really forget the green on the screen. I mean, to your eye it is green and it's sort of a pleasant green you could develop photos with it, but what's so remarkable about ICG is it's potent fluorescence in the near infrared. ↗
▶ Ep 2 · 9:47
clinical Indocyanine green was developed by Kodak company after World War II and has been FDA approved since the 1960s ↗
▶ Ep 2 · 10:30
guideline ICG is approved for all adult and pediatric applications with no on-label or off-label concerns ↗
▶ Ep 2 · 10:40
quote It's a safe, harmless fluorescent contrast. So, uh, you know, there, there's no need for concern for on or off label. It's essentially approved for all things adult and pediatric ↗
▶ Ep 2 · 11:41
clinical ICG is exclusively cleared through the biliary system ↗
▶ Ep 2 · 11:41
quote ICG which is exclusively biliary cleared. So it's hard when you're in and around the liver, but what if you've got liver tissue in another organ space, then instead of giving it when you want it, you give it the day before, it's the only thing left in the chest by the time you get there the next day ↗
▶ Ep 2 · 12:00
clinical For hepatic metastases in the chest, ICG administered 24 hours preoperatively will be retained only in liver tissue by the time of thoracotomy, enabling metastasis localization ↗
▶ Ep 2 · 12:39
clinical Sarcomas other than hepatic primaries require much higher ICG dosage and are less specific ↗
▶ Ep 2 · 12:39
quote All the other sarcomas in the world require a much higher dosage and aren't as specific. ↗
▶ Ep 2 · 13:34
quote Wilms actually in the chest, in the lungs is actually uh avid for ICG, not in the kidney itself, but in the lungs. ↗
▶ Ep 2 · 13:34
clinical Wilms tumor metastases in the lungs are avid for ICG, though the primary kidney tumor is not ↗
▶ Ep 2 · 14:00
clinical ICG fluorescence identifies additional pulmonary metastases beyond what visual inspection and palpation detect during thoracotomy ↗
▶ Ep 2 · 14:00
quote you can spend the requisite time feeling and looking, and then when you're done, if you've given ICG the day before, you'll find more. ↗
▶ Ep 2 · 15:15
quote injectable ICG is not the only future for fluorescence ↗
▶ Ep 2 · 16:20
quote when the stent is emitting an infrared light that gets picked up by your system and you know that that travels through centimeters of tissue. It, it's clear as day. ↗
▶ Ep 2 · 16:20
clinical Infrared ureteral stents emit light that travels through centimeters of tissue and can be detected by standard fluorescence imaging systems ↗
▶ Ep 2 · 17:00
clinical A renally-cleared fluorophore is under investigation that could enable ureteral identification without stent placement ↗
▶ Ep 2 · 17:00
quote this is a new flurofore we are testing that is renally cleared. So what if you could do that without a stent? ↗

Update Course Rewind: Updates in Indocyanine Green (ICG) 2023

▶ Ep 3 · 0:39
clinical ICG is a safe, harmless fluorescent contrast that can be injected subcutaneously or intravenously depending on the use. ↗
▶ Ep 3 · 0:39
clinical Indocyanine Green was discovered by the post-World War II Kodak company and has been FDA approved since the 1960s. ↗
▶ Ep 3 · 0:39
quote Indocyanine Green was this neat dye that uh that the the post World War II Kodak company found because it's got a really pleasant green and so it's been FDA approved since the 1960s. ↗
▶ Ep 3 · 0:39
guideline Sentinel node biopsy at the time of port placement for alveolar rhabdomyosarcoma is pretty much standard of care. ↗
▶ Ep 3 · 0:39
clinical ICG usage has really developed in hepatobiliary surgery. ↗
▶ Ep 3 · 2:12
quote Pediatric surgeons can I'm not yet to the point of saying should but can consider use of ICG as an adjunct to sentinel node identification. ↗
▶ Ep 3 · 2:12
clinical After indocyanine injection into the tumor, ICG travels to the sentinel node over the course of 45, 60, or 75 seconds. ↗
▶ Ep 3 · 2:12
opinion Pediatric surgeons can consider use of ICG as an adjunct to sentinel node identification. ↗
▶ Ep 3 · 2:12
clinical ICG can be used in the operating room with equipment that is either already present or about to be standard in all laparoscopic towers. ↗
▶ Ep 3 · 4:00
clinical Spots detected by ICG in the chest after preoperative administration are also positive on histology. ↗
▶ Ep 3 · 4:00
clinical At the time of thoracotomies for lung metastases, if ICG is given the day before, additional metastases can be found beyond what is detected by palpation and visual inspection. ↗
▶ Ep 3 · 4:00
clinical For detecting liver tissue metastases in the chest, ICG should be given the day before surgery so it is the only thing left in the chest by the time of thoracotomy. ↗
▶ Ep 3 · 4:00
clinical ICG is exclusively biliary cleared. ↗
▶ Ep 3 · 4:00
quote This is a trick of understanding ICG, which is exclusively biliary cleared. So, it's hard when you're in and around the liver. But what if you've got liver tissue in another organ space, then instead of giving it when you want it, you give it the day before. It's the only thing left in the chest by the time you get there the next day. ↗
▶ Ep 3 · 4:46
opinion Fluorescent ureteral stents can enable minimally invasive approaches to cases that would otherwise require open surgery due to ureteral proximity to tumor. ↗
▶ Ep 3 · 4:46
clinical Fluorescent ureteral stents that emit infrared light can be detected by standard laparoscopic systems and help protect ureters during pelvic tumor resection. ↗
▶ Ep 3 · 4:46
quote A case that I'm quite sure would have needed to be done open because of the ureteral proximity to the clearly sticky tumor. ↗
▶ Ep 3 · 4:46
quote So, it's about augmenting the surgeon's visual field and making things safer and better for us. ↗
Seth's statements about Pediatric Oncology 47 statements

Open the Pediatric Oncology collection →

Update Course 2023 - Updates in the use of ICG

▶ Ep 447 · 0:28
quote my understanding was that this distinguished course had already taken on ICG in some of its better known uses, namely organ. Angiography and expatic biliary tree identification. So I was asked to take a little bit of an approach for how, how, how would you use it for pediatric surgical oncology. ↗
▶ Ep 447 · 1:36
guideline Sentinel node biopsy in pediatric rhabdomyosarcoma is standard of care and dictates drug regimen and indicates radiation to lymph node basin if positive ↗
▶ Ep 447 · 1:36
quote This is pretty much standard of care. It, it dictates to some extent the drug regimen. It'll, it'll indicate radiation to the lymph node basin if it's positive. ↗
▶ Ep 447 · 3:16
clinical ICG can be used as an adjunct to sentinel node identification in pediatric surgical oncology ↗
▶ Ep 447 · 3:16
quote pediatric surgeons can, uh, I'm not yet to the point of saying should, but can consider use of ICG as an adjunct to the sentinel node identification ↗
▶ Ep 447 · 4:00
clinical ICG technique allows real-time intraoperative control of injection location (intratumoral vs. four quadrants, dermal vs. subdermal) by surgeons rather than radiologists ↗
▶ Ep 447 · 4:30
quote the ICG technique is real-time in the operating room ↗
▶ Ep 447 · 5:20
clinical ICG fluorescence visualization occurs over 45-75 seconds after injection, allowing direct observation of lymphatic drainage to sentinel node ↗
▶ Ep 447 · 8:40
clinical ICG enables laparoscopic sentinel node identification in paratesticular rhabdomyosarcoma, which is not feasible with radiotracer methods ↗
▶ Ep 447 · 8:40
guideline In children under 10 years old with paratesticular rhabdomyosarcoma, sentinel node biopsy may be performed instead of full ipsilateral lymph node clearance ↗
▶ Ep 447 · 8:40
quote what about the stuff you can't do with technicium like laparoscopy? ↗
▶ Ep 447 · 9:47
quote Into cyanin green was this neat dye that uh that the, the post World War II Kodak company found because it's got really forget the green on the screen. I mean, to your eye it is green and it's sort of a pleasant green you could develop photos with it, but what's so remarkable about ICG is it's potent fluorescence in the near infrared. ↗
▶ Ep 447 · 9:47
clinical Indocyanine green was developed by Kodak company after World War II and has been FDA approved since the 1960s ↗
▶ Ep 447 · 10:30
guideline ICG is approved for all adult and pediatric applications with no on-label or off-label concerns ↗
▶ Ep 447 · 10:40
quote It's a safe, harmless fluorescent contrast. So, uh, you know, there, there's no need for concern for on or off label. It's essentially approved for all things adult and pediatric ↗
▶ Ep 447 · 11:41
quote ICG which is exclusively biliary cleared. So it's hard when you're in and around the liver, but what if you've got liver tissue in another organ space, then instead of giving it when you want it, you give it the day before, it's the only thing left in the chest by the time you get there the next day ↗
▶ Ep 447 · 11:41
clinical ICG is exclusively cleared through the biliary system ↗
▶ Ep 447 · 12:00
clinical For hepatic metastases in the chest, ICG administered 24 hours preoperatively will be retained only in liver tissue by the time of thoracotomy, enabling metastasis localization ↗
▶ Ep 447 · 12:39
clinical Sarcomas other than hepatic primaries require much higher ICG dosage and are less specific ↗
▶ Ep 447 · 12:39
quote All the other sarcomas in the world require a much higher dosage and aren't as specific. ↗
▶ Ep 447 · 13:34
clinical Wilms tumor metastases in the lungs are avid for ICG, though the primary kidney tumor is not ↗
▶ Ep 447 · 13:34
quote Wilms actually in the chest, in the lungs is actually uh avid for ICG, not in the kidney itself, but in the lungs. ↗
▶ Ep 447 · 14:00
quote you can spend the requisite time feeling and looking, and then when you're done, if you've given ICG the day before, you'll find more. ↗
▶ Ep 447 · 14:00
clinical ICG fluorescence identifies additional pulmonary metastases beyond what visual inspection and palpation detect during thoracotomy ↗
▶ Ep 447 · 15:15
quote injectable ICG is not the only future for fluorescence ↗
▶ Ep 447 · 16:20
clinical Infrared ureteral stents emit light that travels through centimeters of tissue and can be detected by standard fluorescence imaging systems ↗
▶ Ep 447 · 16:20
quote when the stent is emitting an infrared light that gets picked up by your system and you know that that travels through centimeters of tissue. It, it's clear as day. ↗
▶ Ep 447 · 17:00
clinical A renally-cleared fluorophore is under investigation that could enable ureteral identification without stent placement ↗
▶ Ep 447 · 17:00
quote this is a new flurofore we are testing that is renally cleared. So what if you could do that without a stent? ↗

Update Course Rewind: Updates in Indocyanine Green (ICG) 2023

▶ Ep 461 · 0:39
clinical ICG usage has really developed in hepatobiliary surgery. ↗
▶ Ep 461 · 0:39
guideline Sentinel node biopsy at the time of port placement for alveolar rhabdomyosarcoma is pretty much standard of care. ↗
▶ Ep 461 · 0:39
clinical Indocyanine Green was discovered by the post-World War II Kodak company and has been FDA approved since the 1960s. ↗
▶ Ep 461 · 0:39
quote Indocyanine Green was this neat dye that uh that the the post World War II Kodak company found because it's got a really pleasant green and so it's been FDA approved since the 1960s. ↗
▶ Ep 461 · 0:39
clinical ICG is a safe, harmless fluorescent contrast that can be injected subcutaneously or intravenously depending on the use. ↗
▶ Ep 461 · 2:12
quote Pediatric surgeons can I'm not yet to the point of saying should but can consider use of ICG as an adjunct to sentinel node identification. ↗
▶ Ep 461 · 2:12
opinion Pediatric surgeons can consider use of ICG as an adjunct to sentinel node identification. ↗
▶ Ep 461 · 2:12
clinical ICG can be used in the operating room with equipment that is either already present or about to be standard in all laparoscopic towers. ↗
▶ Ep 461 · 2:12
clinical After indocyanine injection into the tumor, ICG travels to the sentinel node over the course of 45, 60, or 75 seconds. ↗
▶ Ep 461 · 4:00
clinical ICG is exclusively biliary cleared. ↗
▶ Ep 461 · 4:00
clinical For detecting liver tissue metastases in the chest, ICG should be given the day before surgery so it is the only thing left in the chest by the time of thoracotomy. ↗
▶ Ep 461 · 4:00
clinical At the time of thoracotomies for lung metastases, if ICG is given the day before, additional metastases can be found beyond what is detected by palpation and visual inspection. ↗
▶ Ep 461 · 4:00
clinical Spots detected by ICG in the chest after preoperative administration are also positive on histology. ↗
▶ Ep 461 · 4:00
quote This is a trick of understanding ICG, which is exclusively biliary cleared. So, it's hard when you're in and around the liver. But what if you've got liver tissue in another organ space, then instead of giving it when you want it, you give it the day before. It's the only thing left in the chest by the time you get there the next day. ↗
▶ Ep 461 · 4:46
clinical Fluorescent ureteral stents that emit infrared light can be detected by standard laparoscopic systems and help protect ureters during pelvic tumor resection. ↗
▶ Ep 461 · 4:46
quote So, it's about augmenting the surgeon's visual field and making things safer and better for us. ↗
▶ Ep 461 · 4:46
quote A case that I'm quite sure would have needed to be done open because of the ureteral proximity to the clearly sticky tumor. ↗
▶ Ep 461 · 4:46
opinion Fluorescent ureteral stents can enable minimally invasive approaches to cases that would otherwise require open surgery due to ureteral proximity to tumor. ↗