Surgical management of very early onset inflammatory bowel disease
Topic overview
This retrospective study of 121 VEO-IBD patients found 22% required surgical intervention, most commonly ostomy creation. Black race, diagnosis before age one, severe disease, growth failure, and perianal involvement were significantly associated with need for surgery, while genetic findings and disease location were not predictive.
Key takeaways
- 22% of VEO-IBD patients required surgery; ostomy creation (69%) was more common than bowel resection (35%).
- Black race, diagnosis before age 1, severe disease, growth failure, and perianal disease predict need for surgical intervention.
- Genetic findings and disease location did not significantly correlate with surgical need in this VEO-IBD cohort.
- Post-operative height velocity and medication requirements showed no significant change after resection or stoma creation.
- VEO-IBD predominantly affects colon (63%) with Crohn's phenotype (61%); half of patients transferred from other facilities.
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