CT scan showing large unilateral chest mass displacing the heart in a 10-year-old patient
Slide explaining EWSR1-FLI1 fusion identification in Ewing sarcoma diagnosis using next-generation sequencing.
Flowchart showing Ewing sarcoma treatment pathway from fusion confirmation to chemotherapy protocol.
Blue slide inviting viewers to follow for expert pediatric surgery education content, sponsored by Cincinnati Children's.
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  1. Slide 1: Oncology | Fundamentals | Made possible by Cincinnati Children's | A 10yo with a unilateral chest mass displacing the heart. | WHAT DO YOU NEED BEFORE YOU CAN TREAT? | 1/5
  2. Slide 2: Oncology | Fundamentals | Made possible by Cincinnati Children's | FIRST STEP | NAME IT BEFORE YOU TREAT IT | EWSR1 :: FLI1 | Next-generation sequencing of the biopsy found the EWSR1-FLI1 fusion, the common Ewing sarcoma fusion. | 2/5
  3. Slide 3: Oncology | Fundamentals | Made possible by Cincinnati Children's | NEXT STEP | THE FUSION SET THE TREATMENT | EWSR1-FLI1 FUSION → EWING CONFIRMED → EWING CHEMOTHERAPY | Confirming Ewing sarcoma put the patient on the Ewing chemotherapy pathway: interval-compressed VDC/IE. | 3/5
  4. Slide 4: Oncology | Fundamentals | Made possible by Cincinnati Children's | THE TAKEAWAY: LET THE TUMOR'S BIOLOGY CHOOSE THE TREATMENT | Joseph Pressey, MD | Director, Solid Tumor and Sarcoma Programs, Cincinnati Children's | 4/5
  5. Slide 5: Oncology | Fundamentals | Made possible by Cincinnati Children's | FOLLOW FOR MORE EXPERT-TO-EXPERT PEDIATRIC SURGERY EDUCATION. | 5/5
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Wilms Tumor: A Chest Mass Displacing the Heart

Topic overview

Educational case presentation of Wilms tumor manifesting as a thoracic mass with cardiac displacement. Demonstrates atypical presentation of nephroblastoma requiring multidisciplinary surgical oncology approach in pediatric patients.

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