La búsqueda agresiva de un estado libre de enfermedad (NED) en el hepatoblastoma mejora la supervivencia

Topic overview

Retrospective study of 50 hepatoblastoma patients demonstrates that aggressive surgical pursuit of no evidence of disease (NED) status significantly improves 10-year overall and event-free survival. High-risk patients achieving NED through repeated pulmonary metastasectomy showed survival rates comparable to non-high-risk patients, supporting aggressive surgical intervention strategies.

Key takeaways

Achieving no evidence of disease (NED) status is essential for survival in hepatoblastoma patients
Aggressive surgical pursuit of NED improves 10-year overall survival and event-free survival regardless of risk stratification
High-risk patients achieving NED have similar 10-year survival to non-high-risk patients (no significant difference, p=0.83)
Repeated pulmonary metastasectomy (median 2.5 procedures) can achieve long-term survival in high-risk hepatoblastoma
82% of patients achieved NED status; NED correlated inversely with 5-year mortality (OR 0.006, p<0.01)

Keywords

Hepatoblastoma Metastasectomía Pulmonar Oncología Pediátrica Cirugía Hepática Enfermedad Residual Tumores Hepáticos Pediátricos Pediatric Oncology Metastasectomy Surgical Oncology Liver Tumors Pulmonary Metastases No Evidence Of Disease

Hashtags

#Hepatoblastoma #CirugaOncolgica #OncologaPeditrica #MetastasectomaPulmonar #PediatricOncology #SurgicalOncology #LiverTumors

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